Genomic Services
1.1 M+
annual cases of cancer in Africa and over 60% mortality.
This growing burden is compounded by a lack of precision diagnostic tools for early detection, categorization and treatment. Metaphor’s genomic services harness the power of Next-Generation Sequencing (NGS) to provide insights that drive the development of new therapies, diagnostics and personalized treatment plans.
Next-Generation Sequencing (NGS)
Our NGS services enable comprehensive genomic analysis to support research and clinical diagnostics.
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Whole Genome Sequencing (WGS)
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Whole Exome Sequencing (WES)
Focused sequencing of exonic regions to detect variants associated with diseases.
Targeted Sequencing
Custom panels designed to target specific genes or regions of interest.
Copy Number Variation (CNV) Analysis
Detecting large genomic alterations that could contribute to disease.
Single Nucleotide Variation (SNV) Detection
Identifying single nucleotide changes that may have clinical relevance.
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Insertions/Deletions (Indels)
Detecting small insertions and deletions in the genome that could impact gene function.
Gene Expression Profiling
Whether you’re developing new diagnostic tools or exploring the molecular basis of disease, our high-throughput gene expression analysis can support your research with insights into gene activity in various conditions.
NGS-Based RNA Sequencing
Find out which genes are actively being transcribed into RNA, and at what levels. Discover novel transcripts, alternative splicing events, and gene fusions for complex biological research and clinical diagnostics.
Single-Cell RNA Sequencing
Get unparalleled insights into cellular diversity for oncology and immunology research through analysis of gene expression at the individual cell level.
qPCR Validation
Precisely quantify individual gene expression levels to validate key findings from NGS and for focused studies on specific genes of interest.
Bioinformatics
Process raw data, normalize it, and identify significant differentially expressed genes.
Genomic Assay Development and Validation
We specialize in developing and validating genomic assays.
Assay Transfer
We support the transfer and validation of FDA-approved NGS- based diagnostic panels to our lab. Our expertise and positioning allow us to cost-effectively scale genomic assays for broader use.
Custom Assay Development
We can design assays that target specific genetic markers, mutations, or gene expression profiles, ensuring they meet the highest standards of sensitivity, specificity, and regulatory compliance.
Inclusive Validation Services
We perform rigorous testing to confirm that assays perform reliably across different sample types and populations.
Integrating genomics with other services.
Our genomic services are seamlessly integrated with our biomarker solutions and assay development to provide a comprehensive approach to diagnostics. By combining genomic insights with biomarker data, we enable our clients to advance their R&D efforts and clinical diagnostic capabilities for more personalized and effective treatments.
Sample handling and processing
We accept a wide range of sample types
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DNA Extracts
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FFPE Tissue Blocks
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Blood and Biofluids
Workflow
DNA Extraction
Library Preparation
NGS Analysis
Data Analysis
Report Generation
