Assay Development

Elevating diagnostic precision with advanced assay development

Africa’s vast genetic diversity is the highest in the world. Metaphor leverages this to develop cost-effective, robust diagnostic assays tailored to the region. We address critical diagnostic insufficiencies while collaborating with global innovators to integrate Africa’s population into their diagnostic innovations for broader applicability.

Design And Feasibility Studies

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Our services cover an extensive range of assay formats

Molecular Assays (PCR, qPCR)

Precision genetic testing to identify pathogens or genetic mutations.

Liquid Biopsy Assays

Biomarker analysis in blood or other body fluids to detect cancer and monitor disease progression non-invasively.

Lateral Flow Assays

Ideal for rapid, point-of-care testing.

ELISA

For highly sensitive detection of antigens or antibodies.

From Concept to Reality

We begin with a deep dive into the client’s requirements. Our R&D team conducts thorough feasibility studies to assess various assay formats and methodologies and ensure that the proposed assay aligns perfectly with the diagnostic goals.

Crafting the perfect assay

Once the design is finalized, our skilled scientists develop and optimize the assay to ensure it meets all performance criteria. This phase includes:

Primer and Probe Design

Protocol Development

Prototype Development

Ensuring reliability 

Validation is critical to the reliability and regulatory compliance of diagnostic assays. At Metaphor, we adhere to guidelines from the FDA, CAP and ISO.

Sensitivity and Specificity Testing

Robustness and Reproducibility

Comprehensive Documentation

Expertise and advanced technologies

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Our capabilities

Next-Generation Sequencing (NGS)
Bioinformatics

Cutting-Edge Platforms  

Our state-of-the-art technology platforms support high-throughput screening, multiple readout options, and a wide array of diagnostic applications.

Our bioanalytical research experts specialize in assay development, validation and sample analysis. We support our partners from discovery through clinical Phase IV trials and are dedicated to our mission of saving lives through precision diagnostics.